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Top Six Benefits of Selenium


Did you know that selenium, an essential mineral, has the ability to protect your health in multiple ways?

Selenium is an important mineral for your body and only a small amount is needed (the recommended daily intake is 55 micrograms (mcg). Due to poor soil, taking certain pharmaceutical drugs such as statins, and the normal aging process, selenium is one of the most common mineral deficiencies in the world.

Selenium is linked to many healthy outcomes, including protection from diseases and reduction of disease symptoms. 

Six Top Benefits of Selenium

1. Antioxidant and Reduces Oxidative Stress

As an antioxidant, selenium is even more beneficial than vitamins A, C, D, and E and helps to decrease oxidative stress, which is the result of an imbalance in the body between free radicals and antioxidants.

Oxidative stress contributes to a variety of diseases such as diabetes, atherosclerosis (hardening of the blood vessels), inflammatory conditions, high blood pressure, heart disease, neurodegenerative diseases (such as Parkinson’s and Alzheimer’s), and cancers, and contributes to aging.

Supplementing with selenium was reviewed in 13 studies showing significant impact on three antioxidant markers, thus reducing oxidative stress.

2. Boosts Skin Health

In a meta-analysis of 27 studies with a total of 1,315 patients and 7,181 healthy controls, selenium levels were found to be low in patients with four skin diseases: psoriasis, acne vulgaris, chloric acne, and atopic dermatitis.

Another research study of DNA reprogramming of inflammatory cells confirms that higher selenium levels may instill protective properties for genes important for psoriasis prevention and treatment.

Selenium was also found to be beneficial in the treatment of psoriasis in a systematic review of research. In addition, selenium has been related to improvements in skin aging (skin elasticity and skin roughness).

Blood glutathione peroxidase (low levels indicate increased damage to cell membranes due to accumulation of free radicals and signify low selenium levels) was measured in 61 healthy subjects and 506 patients with various skin disorders (i.e., psoriasis, eczema, atopic dermatitis, vasculitis, mycosis fungoides and dermatitis herpetiformis, pemphigoid, acne conglobata, polymyositis, rheumatoid arthritis, scleroderma, and systemic lupus erythematodes) and supplementation with selenium and vitamin E restored the skin’s balance.

3. Benefits Asthma

Asthma (a condition with breathing difficulties, coughing, and sneezing) is a complicated disease to treat and is associated with increased inflammation, oxidative stress, and abnormal immune system function. In a meta-analysis of 40 studies, asthma patients showed significantly lower levels of selenium compared to healthy subjects, suggesting lower selenium intake could be a risk factor for the disease.

As mentioned, selenium, as an antioxidant, has been found to lower oxidative stress. This, in turn, seems to reduce allergic asthma. In addition, dietary selenium as an antioxidant therapy may be important in optimizing asthma treatment and prevention.

In a study of 25 asthmatic patients and 25 healthy subjects, asthmatics had lower concentrations of selenium, increased oxidative stress markers and inflammation, and decreased antioxidant glutathione peroxidase activity and lung function.

Nutritional supplement therapy including selenium balanced oxidant stress, inflammation and immune system responses, pulmonary function, and health-related quality of life in patients with mild to moderate allergic asthma.

4. Helps Prevent and Improve Thyroid Diseases

Selenium is an essential micronutrient for your body and readily found in the thyroid. As a supplement, it can help prevent immune-mediated thyroid disorders by reducing anti-thyroperoxidase antibody levels and improving thyroid ultrasound features.

The prevalence of pathological thyroid conditions (hypothyroidism, subclinical hypothyroidism, autoimmune thyroiditis, enlarged thyroid) was significantly lower in the adequate-selenium group than in the low-selenium group (18% versus 30.5%) in a sample of 6,152 subjects in China.

Selenium administration (200 milligrams per day) significantly improved quality of life, reduced ocular involvement, and slowed progression of 159 patients with mild Graves’ orbitopathy (also called thyroid eye disease).

5. Promotes Heart Health

The combination of high blood pressure, high blood sugar, obesity, and high cholesterol is called metabolic syndrome and when these conditions occur together, they dramatically increase your risk of heart disease, stroke, and Type 2 diabetes.

In a study of 2,069 patients, dietary selenium intake had a moderate negative association with metabolic syndrome. In a study of 501 British volunteers aged 60 to 74 years, supplementation with selenium (100 mcg, 200 mcg, 300 mcg) showed progressive decreases in total cholesterol profiles for those with low selenium levels, but cautions that those with already high selenium intake might be adversely affected by extra selenium supplementation.

In a 12-year follow-up of a group of healthy elderly participants who were supplemented with selenium and coenzyme Q10 for four years, there was a significantly reduced risk for cardiovascular mortality in the treatment group (28.1%) compared to the placebo group (38.7%).

6. Brain Boosting

Alzheimer’s disease, a devastating brain disorder, is characterized by two pathological protein deposits, the senile plaques of amyloid-β and tangles of protein tau. In addition, oxidative stress and neural signal transmission disorders also impact Alzheimer’s.

A large body of studies suggests that selenium (Se), either as Se-containing compounds or as selenoproteins, is involved in most of the molecular pathways that are important in the progression of dementia and therefore have the potential to help prevent or improve Alzheimer’s.

In a mouse model, selenium yeast showed several benefits for Alzheimer’s subjects; it decreased the generation of amyloid-β and enhanced autophagic clearance (old cells are recycled and cleaned out to make room for new cells in the brain), which reduced the burden of amyloid-β accumulation.

Another animal study confirmed that selenium (sodium selenite) significantly decreased tau-positive neurons and reversed Alzheimer’s-like memory and neuropsychiatric symptoms in mice with advanced dementia. Additionally, selenium induced protective effects against experimental dementia-induced brain inflammation and oxidative stress by enhancing the antioxidant system in rats.

In 79 Alzheimer’s patients, probiotic and selenium co-supplementation for 12 weeks improved cognitive function and some metabolic profiles such as lipid, antioxidant, and insulin levels.  Selenium and zinc are essential trace elements and an inadequate dietary intake has been implicated in the decline of immune and cognitive functions in aged persons and influences age-related disorders, such as Alzheimer’s and Type 2 diabetes.

Selenium and Health

Selenium, a widely researched essential mineral, is beneficial to your health due to its antioxidant, anti-inflammatory, neuroprotective, immunomodulatory (regulates immune functions) and cardioprotective properties.

Be sure to pick up your Selenium Supplement on your next visit to Whitaker’s Natural Market!

Portions of this Health Tip are from GreenMedInfo.

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I wanted to share a recent study with you on protective benefits against Alzheimers…

More berries, apples, and tea may have protective benefits against Alzheimer’s – Study shows low intake of flavonoid-rich foods linked with higher Alzheimer’s risk over 20 years.

Older adults who consumed small amounts of flavonoid-rich foods, such as berries, apples, and tea, were 2 to 4 times more likely to develop Alzheimer’s disease and related dementias over 20 years compared with people whose intake was higher, according to a new study led by scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University.

The epidemiological study of 2,800 people aged 50 and older examined the long-term relationship between eating foods containing flavonoids and risk of Alzheimer’s disease (AD) and Alzheimer’s disease and related dementias (ADRD). While many studies have looked at associations between nutrition and dementias over short periods of time, the study published today in the American Journal of Clinical Nutrition looked at exposure over 20 years.

Flavonoids are natural substances found in plants, including fruits and vegetables such as pears, apples, berries, onions, and plant-based beverages like tea and wine. Flavonoids are associated with various health benefits, including reduced inflammation. Dark chocolate is another source of flavonoids.

The research team determined that low intake of three flavonoid types was linked to higher risk of dementia when compared to the highest intake. Specifically:

• Low intake of flavonols (apples, pears, and tea) was associated with twice the risk of developing ADRD.

• Low intake of anthocyanins (blueberries, strawberries, and red wine) was associated with a four-fold risk of developing ADRD.

• Low intake of flavonoid polymers (apples, pears, and tea) was associated with twice the risk of developing ADRD.

The results were similar for AD.

“Our study gives us a picture of how diet over time might be related to a person’s cognitive decline, as we were able to look at flavonoid intake over many years prior to participants’ dementia diagnoses,” said Paul Jacques, senior author and nutritional epidemiologist at the USDA HNRCA. “With no effective drugs currently available for the treatment of Alzheimer’s disease, preventing disease through a healthy diet is an important consideration.”

The researchers analyzed six types of flavonoids and compared long-term intake levels with the number of AD and ADRD diagnoses later in life. They found that low intake (15th percentile or lower) of three flavonoid types was linked to higher risk of dementia when compared to the highest intake (greater than 60th percentile). Examples of the levels studied included:

Low intake (15th percentile or lower) was equal to no berries (anthocyanins) per month, roughly one-and-a-half apples per month (flavonols), and no tea (flavonoid polymers).

High intake (60th percentile or higher) was equal to roughly 7.5 cups of blueberries or strawberries (anthocyanins) per month, 8 apples and pears per month (flavonols), and 19 cups of tea per month (flavonoid polymers).

“Tea, specifically green tea, and berries are good sources of flavonoids,” said first author Esra Shishtar, who at the time of the study was a doctoral student at the Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University in the Nutritional Epidemiology Program at the USDA HNRCA. “When we look at the study results, we see that the people who may benefit the most from consuming more flavonoids are people at the lowest levels of intake, and it doesn’t take much to improve levels. A cup of tea a day or some berries two or three times a week would be adequate,” she said.

Jacques also said 50, the approximate age at which data was first analyzed for participants, is not too late to make positive dietary changes. “The risk of dementia really starts to increase over age 70, and the take home message is, when you are approaching 50 or just beyond, you should start thinking about a healthier diet if you haven’t already,” he said.

Be sure to shop for your organic flavonoids on your next visit to Whitaker’s Natural Market.

Portions of this health tip are from NewHope.